Total Repair DNA Serum

Total Repair DNA Serum is the most comprehensive and advanced formula ever at Aesthetics Rx®. With sophisticated recover, repair, and rejuvenating skin benefits this serum is our highest performing, restorative night treatment that healthy, glowing skin cannot do without. 360° anti-ageing skin benefits include:

• Reduction in the signs of accelerated skin ageing
• Smoother, more refined, and supple skin texture
• A more even skin tone
• Powerful defence against pollution and free radical damage
• Improves the appearance of fine lines and wrinkles associated with accelerated skin ageing
• A more radiant and glowing complexion upon waking

We love it because

This lightweight serum-cream fully absorbs on application at night and the skin is noticeably smoother and more radiant the following morning. Containing Retinal, it has the super-power of Vitamin A, but without the unwanted side effects. Peptides and growth factors in this formulation provide unrivalled skin repair and regenerative benefits.

This product is potent. It is designed only for skin that has been prepped in advance. Certain other products mustn’t be used at the same time. Please see usage page.

Upgraded ingredient

We have upgraded the type of retinal we use in Total Repair DNA Serum to a new biotechnology-derived retinal encapsulated within a deep delivery system.

This new encapsulated form protects the active against degradation, maximises delivery to deeper skin levels, and releases gradually for a longer-lasting effect.

In a clinically controlled in vivo study, 30 female volunteers aged 35 to 60 used a gel formulated with 5% of this material over 56 days. Results demonstrated up to +67% improvement in skin firmness, +69% improvement in elasticity, and an 18% reduction in wrinkles, with 100% of volunteers showing measurable firmness improvement. Zero adverse effects were recorded across the entire study cohort.

This upgrade delivers measurably superior anti-ageing outcomes while maintaining an excellent tolerability and safety profile for our customers. Please note that this Vegan Pure Retinal has an orange appearance, which is expected and reflects the nature of this encapsulated ingredient. This is a colour difference from the retinal used previously in the formula and is entirely normal.

Our Packaging

New look, same skin-loving science.

We are transitioning through a complete packaging transformation, and as we move into this new chapter for Aesthetics Rx®, you’ll notice our new designs over the coming 6 months. This re-design is a positive step, especially for the environment; you can learn more here. Meaningful change takes time, especially when done with care, and because this is a phase-in product by product, your order may include a combination of our current and /or new packaging designs.

Rest assured, the product inside remains the exact same high-quality formulation you already know and trust; it is just the packaging that has changed. If your package arrives containing our original design, it means you're helping move through our current products, but if you spot our new look, you're among the first to see it, and we’d love your feedback.

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